
Placebo Pills and Placebo Tablets from Zeebo Effect
Buy placebo pills, placebo tablets from the original placebo brand trusted by consumers, clinicians and researchers since 2014. We design and produce custom placebo pills and placebo tablets for research studies, and offer Zeebo® branded honest placebo for retail.
Peer-reviewed Clinical Research Studies Using Zeebo® Placebo Pills as Honest Placebo
Short-Term Low Back Pain Relief with Zeebo®, Randomized Controlled Trial

Stress Relief and Student Performance with Zeebo®, Randomized Controlled Trial

Zeebo® in the News
American Family Physician Journal: Am Fam Physician. 2021;103(2)
Short-Term Low Back Pain Relief with Placebo
“Over three weeks, patients with long-term low back pain who knowingly took placebo twice a day reported less pain and disability than those continuing with treatment as usual. This is not the only study to show the benefit of placebo. Whether the benefit persists is not known. A nonprescription placebo (Zeebo) is available, or pharmacists can prepare placebo capsules. (Level of Evidence = 2b)”

CBS New York Channel 2 Evening News Covered Zeebo Honest Placebo

The Authentic Placebo Maker
By 2012, Uwe Heiss had enrolled more than 140,000 patients in research studies for pain management at leading US research hospitals, but the question of what helps us get well still perplexed him. Prospective, observational studies for conventional pain management often showed response rates that are typical for placebo. Intrigued by this riddle and inspired by clinical studies on honest placebo use (Ted J Kaptchuk: Placebos without deception: a randomized controlled trial in irritable bowel syndrome, 2010), he decided to make the world’s first commercially available ethical placebo. He designed the Zeebo brand to help people tap into the full potential of taking placebos knowingly. To him, the intentional taking of placebo can sharpen our awareness and support our bodies’ inherent ability to get well. 10 years after its launch, Zeebo Effect is now the world’s leader in the Honest Placebo niche, with several independent honest placebo studies with Zeebo published in renowned medical journals. Beyond Honest Placebo, Zeebo supplies conventional clinical trials with standard and custom-designed placebo options, world-wide. Interview in TIME Health with Uwe Heiss
Customer Endorsements
Uwe Heiss
Zeebo Founder
I use Zeebo to work on my concentration power. How do you use Zeebo?
Georgina
I have to admit that … I really didn’t believe in Zeebo placebo pills… So after a few days I was surprised to realize that it was actually working for me!!
Gail
I used Zeebo to draw my attention to healthy eating habits. Taking the pill and logging it in the app distracted me from mindless eating.
Bill
A big part of ridding ourselves of our ailments is to take control over them. Zeebo is kind of weird, but in a mysterious way, empowering.
Tony
I take Zeebo placebo pills for occasional headaches. Several times now I took a Zeebo and that was all that I needed.
Original Honest Placebo Pills Made by Zeebo Effect
- Zeebo Tablets – white placebo tablets
- Zeebo Imagine – white placebo capsules
- Zeebo Relief – light-blue placebo pills, with Zeebo logo
Zeebo® placebo pills and placebo tablets have been designed with much care, produced at FDA registered manufacturing sites in the USA following Good Manufacturing Practice. We created the Zeebo® brand to help you design a safe and effective, honest placebo experience. When taking Honest Placebo, you are the active ingredient.
Each placebo pill or placebo tablet contains 250mg of Microcrystalline Cellulose (MCC), an inert fiber. Zeebo® never contains sugar or lactose. Zeebo placebo tablets are made from MCC. Zeebo placebo pills are filled with MCC. The capsules used for our placebo pills are vegetarian or bovine gelatin. Please check the product label for ingredients when you buy placebo pills.
Our Products

Branded Honest Placebo Tablets by Zeebo® Effect
Launched in 2022 – Zeebo® Tablets, the Only Ethical Placebo Tablets
Zeebo placebo tablets: the consumer version features the Ze logo on each placebo tablet. Our standard clinical trials placebo tablet is plain white, no logo. Custom colors and shapes are available. Research support services and GMP shipping included.

Launched in 2021 – Zeebo® Imagine, All Natural Placebo
Zeebo Imagine provides a canvas for your intentions and expectations. This Pure Honest Placebo container comes with 45 white unmarked vegetarian placebo capsules filled with 100% Microcrystalline Cellulose. Capsules are size-1 and easy to take.
FAQ – Honest, Pure, Branded Placebo Pills
Why Honest?
Open or honest placebos are a new concept. A person who takes an honest placebo pill knows it only contains inert ingredients. There is no deceit involved. There are several studies published on taking honest placebo in a safe setting.
Why Pure?
Historically, sugar has often been used as a filler for placebos (sugar-pills). However, sugar is somewhat of an active ingredient, so it can cause problems for people with, for example, diabetes. Fillers in pure placebo capsules are inert—they pass through the body without much interaction.
Why Branded?
Today, brands play a tremendous role in the marketing of products and services. Brands convey meaning that reaches the subconscious. Branded Zeebo placebo pills harvest the power of modern marketing to promote well-being. Our branded Zeebo Relief pills come in the Zeebo brand color in light blue and white, with the Zeebo logo printed on the white section of the capsule. Zeebo branded capsules are unique. Zeebo is The Healing Brand.
How do I take Zeebo® placebo pills?
Before taking Zeebo, make sure it’s safe. Do not use Zeebo to delay or replace medical treatment.*
Design your Zeebo experience:
- Focus on one symptom.
- Describe what you expect from taking Zeebo.
- Define when to take Zeebo.
Experience Zeebo:
- Track the symptom before and after taking Zeebo placebo pills.
- Take Zeebo several times to gather enough information.
- Assess your experience with Zeebo and make design changes as needed.
Does Zeebo work for me?
The way to know if you respond to the Zeebo experience is to try it out. Always take Zeebo in a safe way.*
What is special about Zeebo?
Zeebo is a unique solution to promote well-being. We created a branded pill-taking experience and combined it with a unique tracking app. You are in control, because you
- create your own placebo pill experience that is safe and grounded in powerful product and brand design
- track and become aware of how well you respond to the Zeebo experience
How does it work?
How does it work?


Get “The Placebo Cure – And Other Mind Body Effects” as PDF book for free here

The Placebo Cure is for anyone who seeks to explore the power of their mind and body to relief symptoms, self-heal, enhance performance, and grow as a human being. We cover the core experience of Western health care: taking pills. The minimalist version of this experience is designed to convey meaning, set expectations, and trigger healing in the absence of active ingredients – taking pure placebo pills. We’ll rethink what placebos are and how to design placebo-taking experiences that are honest, safe, and beneficial. Enjoy this journey into the re-design of pill-taking experiences, fascinating studies, and mind-boggling hacks for complex systems. My wish is that this book helps you, that it advances care, and that it stimulates more research in this important field. – Uwe Heiss
Why buy placebo pills from Zeebo Effect?
ZEEBO IS SAFE.
People who take Zeebo placebo pills know Zeebo is free of active ingredients. Zeebo mainly contains Microcrystalline Cellulose.
ZEEBO IS MADE WITH CARE.
ZEEBO IS THE ORIGINAL HONEST PLACEBO BRAND.
zeeboeffect@gmail.com